신소재공학과

Seminar

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Date 20190326

■ Title :  Materials science-based approach to brain research

           

■ Speaker :  Prof. Jae-Byum Chang (KAIST MSE)

 

■ Date and Time :  3/26(Tue) 16:00

 

■ Venue :  Applied Engineering Building (W1) 1st Floor, Multimedia Lecture Room

 

 Abstract : 

Visualization of molecules inside cells and organs has been the biggest challenge in biological sciences and medicine. Recently, various optical microscopy techniques have been developed to overcome this challenge. Interestingly, these new techniques were developed based on the knowledge of material properties of organs. For example, various organ clearing techniques (iDISCO, CUBIC, SeeDB, CLARITY) clear organs and make them transparent, enabling large-volume optical imaging without thin-sectioning. These clearing techniques use refractive index-matching solutions to minimize the light scattering inside organs. Second example is organ expansion technique (expansion microscopy), in which organs are physically expanded, enabling super-resolution imaging of organs with conventional diffraction-limited optical microscopy. This technique uses a swellable hydrogel to uniformly expand organs. In this talk, recently developed organ clearing and expansion techniques are introduced. Their mechanisms are explained and compared.

   


List of Articles
No. Category Subject Author Date Views
Notice Regular 6/4 (Tue) Prof. SangBum Kim (Dept. of MSE, SNU) ADMINI 2019.05.31 477
Notice Regular 5/28 (Tue) Prof. Seok Su Sohn (Dept. of MSE, Korea Univ.) ADMINI 2019.05.24 446
Notice Regular 5/21 (Tue) Emeritus Prof. Joong Keun Park (Dept. of MSE, KAIST) ADMINI 2019.05.17 454
Notice Regular 5/17 (Tue) Prof. Su-Hyun Gong (Dept. of Physics, Korea Univ.) ADMINI 2019.05.10 950
Notice Special 5/7 (Tue) Prof. Dr. -ing. Dierk Raabe (MPIE) ADMINI 2019.04.30 763
Notice Regular 4/30 (Tue) Prof. Min Hyuk Park (School of MSE, Pusan National Univ.) ADMINI 2019.04.25 547
Notice Regular 4/23 (Tue) Prof. Seungwu Han (Dept. of MSE, SNU) ADMINI 2019.04.19 308
11 Special 11/14 (Wed) Prof. Hui-Ming Cheng (Director and Professor, Tsinghua University, IMR CAS) ADMINI 2018.11.13 628
10 Regular 11/20 (Tue) Prof. Youn Soo Kim (Department of MSE, POSTECH) ADMINI 2018.11.19 963
9 Regular 11/27 (Tue) Prof. Seong-Jun Jeong (Soongsil Univ.) ADMINI 2018.11.26 873
8 Regular 12/4 (Tue) Prof. Doo Seok Jeong (Hanyang Univ., Department of MSE) ADMINI 2018.11.30 1563
7 Special 1/28 (Mon) Prof. Yongjin Lee (Shanghai Tech Univ.) ADMINI 2019.01.23 813
6 Regular 2/26 (Tue) Dr. Hye-Young Kim (Senior Venture Association) ADMINI 2019.02.22 557
5 Regular 3/12 (Tue) Prof. Chang Dong Yoo (KAIST EE) ADMINI 2019.03.12 417
4 Regular 03/19 (Tue) Dr. YangKoo Cho (Korea Research Institute of Standard and Science) ADMINI 2019.03.18 447
» Regular 03/26 (Tue) Prof. Jae-Byum Chang (KAIST MSE) ADMINI 2019.03.22 552
2 Regular 4/2 (Tue) Prof. Li Oi Lun (Dept. of MSE, Pusan National Univ.) ADMINI 2019.03.29 281
1 Regular 4/9 (Tue) Prof. Ji Young Jo (GIST, School of MSE) ADMINI 2019.04.05 274
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